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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD4
All Species:
31.52
Human Site:
Y477
Identified Species:
63.03
UniProt:
Q9Y227
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y227
NP_001122402.1
616
70255
Y477
E
R
F
D
R
G
L
Y
A
S
H
A
D
L
H
Chimpanzee
Pan troglodytes
XP_519659
710
80224
Y571
E
R
F
D
R
G
L
Y
A
S
H
A
D
L
H
Rhesus Macaque
Macaca mulatta
XP_001108472
728
82237
Y589
E
R
F
D
R
G
L
Y
A
S
H
A
D
L
H
Dog
Lupus familis
XP_543243
608
69462
Y469
E
R
F
D
R
G
L
Y
A
S
H
A
D
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBT4
613
69727
Y477
E
R
F
D
R
G
L
Y
A
S
H
A
D
L
H
Rat
Rattus norvegicus
P97687
511
57389
V377
K
K
M
A
N
D
S
V
S
S
Q
E
K
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507040
633
71884
Y493
E
R
F
D
R
G
L
Y
A
S
H
A
D
L
H
Chicken
Gallus gallus
P79784
495
54515
E361
D
F
I
R
T
V
M
E
R
P
V
H
S
P
S
Frog
Xenopus laevis
NP_001088548
616
70594
Y477
E
R
F
D
R
G
L
Y
A
S
H
A
D
L
H
Zebra Danio
Brachydanio rerio
NP_001002419
611
69763
Y469
E
R
F
D
R
G
L
Y
A
S
H
A
D
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21815
552
62492
L418
P
R
A
D
E
E
R
L
R
T
Q
C
F
K
S
Sea Urchin
Strong. purpuratus
XP_785341
537
60729
Q402
P
V
L
G
S
N
K
Q
C
Q
K
E
P
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
82.2
93.5
N.A.
93
26.4
N.A.
86.5
24.5
77.1
70.6
N.A.
N.A.
N.A.
30.6
48.5
Protein Similarity:
100
85.4
82.8
96.4
N.A.
97.5
47.4
N.A.
92
42.6
88.4
84.2
N.A.
N.A.
N.A.
48.8
63.3
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
0
100
93.3
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
100
13.3
100
93.3
N.A.
N.A.
N.A.
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
0
0
67
0
0
67
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
9
0
9
0
% C
% Asp:
9
0
0
75
0
9
0
0
0
0
0
0
67
0
0
% D
% Glu:
67
0
0
0
9
9
0
9
0
0
0
17
0
0
0
% E
% Phe:
0
9
67
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
9
0
67
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
67
9
0
0
67
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
0
0
0
9
0
0
0
9
0
9
9
0
% K
% Leu:
0
0
9
0
0
0
67
9
0
0
0
0
0
59
0
% L
% Met:
0
0
9
0
0
0
9
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
17
0
0
0
0
0
0
0
0
9
0
0
9
9
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
9
17
0
0
9
0
% Q
% Arg:
0
75
0
9
67
0
9
0
17
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
9
0
9
75
0
0
9
0
25
% S
% Thr:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
9
% T
% Val:
0
9
0
0
0
9
0
9
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _